PNAS: Enhance immunity? Come to vitamin D!
Release date: 2015-06-23 June 18, 2015 - Vitamin D plays an important role in the body's immune response. Vitamin D deficiency can reduce the immunity of individuals against multiple infections, such as HIV-1, now published in the international magazine PNAS . In a research paper, researchers from Penn State University have revealed that high doses of vitamin D supplements can reverse the immune response of the body, but can enhance the body's immune response. In the article, researcher Nina Jablonski said that vitamin D supplementation is a simple and effective intervention that can effectively reduce the risk of HIV-1 infection and disease progression in individuals, especially in resource-poor areas; The researchers studied two ethnic groups living in South Africa to observe how UV-B radiation, dietary vitamin D, genetic factors, and pigmentation caused by seasonal differences affect individual vitamin D levels, and researchers also studied high. How do doses of vitamin D supplements improve the body's resistance to HIV-1 immunity? Cape Town is a western city in South Africa with seasonal UV-B exposure and is one of the regions with the highest HIV-1 infection rate in the world. In the article, the researchers divided healthy young individuals into two groups. The group is the ancestors of the Khosa, that is, their ancestors migrated from the vicinity of the equator to life in Cape Town, while the other group is a mixed-race group, that is, the mixed population of the Khosa, Europe, South Africa, etc.; Exposure to more UV radiation is the most serious form of melanin in the skin. The researchers said that skin pigmentation is more serious, which means that there is enough ultraviolet radiation to induce the body to produce vitamin D precursor substances; after studying the two groups of subjects, the researchers found that these individuals in the winter when the body appears Vitamin D is missing. On average, women are more likely to be missing than men. Because vitamin D has a certain impact on the body's immune system, the researchers asked 30 Cosa people to take vitamin D3 supplements for up to 6 weeks, which can help 77%. The individual improves the level of vitamin D in the body. Subsequently, in order to detect the state of vitamin D affecting the body's immune system response to HIV-1, the researchers collected the participants' blood samples in winter and summer, and analyzed the blood samples when the participants' vitamin D was adequate and missing. The results showed that the HIV-1 infection rate of blood samples collected in winter was significantly higher than that in summer, and after taking 6 weeks of vitamin D supplements, the researchers found that HIV infection levels in the blood samples of the Kosa population and A consistent level was shown during the summer. Finally, the researchers said that high doses of oral vitamin D3 supplements slowed the replication of HIV-1, increased white blood cell circulation in the body's blood and reversed individual winter-related anemia, and vitamin D3 significantly improved the body's HIV-associated immunity. force. Source: Bio Valley Soft Bandages,Cotton Bandages,Medical Bandages,First-Aid Plaste Bandage Zhende Medical Co.,Ltd , https://www.zdmedicalproduct.com