2014 global new breakthrough gene technology events
Gene technology is the core of modern biotechnology. The revolutionary results of genetic technology in gene pharmacy, gene diagnosis, gene therapy and other technologies have greatly changed the face of human life and life, which has aroused people's heated discussion. The business value is even more incalculable, and it has also attracted the attention of investors. What new breakthroughs in genetic technology in 2014? This article will provide a detailed combing of disruptive technologies. According to the collected data, it is found that the future gene technology will mainly develop in five major directions: 1. Develop new biotechnology products such as peptides, proteins and nucleic acids for major diseases such as nervous system, tumor, cardiovascular system, AIDS and immunodeficiency; 2. Select a batch of biotechnology products with good market prospects, vaccines and monoclonal antibodies for diagnosis, and focus on hepatitis B gene vaccine and monoclonal antibody diagnostic reagents; 3, the development of targeted drugs is mainly the development of anti-tumor drugs, the current treatment of cancer drugs does exist a so-called "enemy and me". While killing cancer cells, it also kills normal cells. Guided treatment is proposed for this problem. The so-called guided therapy is to use antibodies to find targets, such as the missile navigator, to accurately introduce drugs into the lesion without harming other tissues and cells; 4. Research and development of humanized monoclonal antibodies. Antibodies can be used against a variety of pathogens, and can also act as a guide, but the current monoclonal antibodies, mostly murine antibodies, are themselves considered antigens by xenogeneic organisms and induce antibodies (anti-antibodies) when injected into humans. Or stimulate the immune response. At present, phage antibody technology, chimeric antibody technology, and genetic engineering antibody technology have been studied abroad to solve the problem of humanized antibodies; 5. The research and development of blood substitutes still occupy an important position. Blood products are made from a large number of mixed human plasma. Since human blood is inevitably contaminated by various pathogens, such as HIV and hepatitis B virus, blood transfusions can be used to infect people who receive blood transfusions with HIV or hepatitis B. Occurs, so the use of genetic engineering to develop blood substitutes is eye-catching; 2014 new breakthrough research on gene technology December Gene Recombination Technology Brings Green Silkworm Baby Japanese researchers use a new technology of genetic recombination to make silkworms glow green. The new technology of genetic recombination developed by Professor Yamamoto and others at Hiroshima University in Japan is called "PITCh method", which mainly utilizes an enzyme capable of cutting a specific gene in a genome and a mechanism for repairing damaged DNA (deoxyribonucleic acid) by a living organism. New gene knock-in technology enables the introduction of foreign genes. Researchers from Hiroshima University have used a novel gene knock-in technology to achieve efficient introduction of foreign genes into the genome. Currently, the technology has been used in human cells. Animal models such as frogs and silkworms have been successfully implemented. This technology not only enables the insertion of genes in culture, but also the insertion of foreign genes in a variety of organisms. Personally exclusive anti-aging skin care products, Chris, Professor of Imperial College, London, UK? Tumazzo has used his invented microchip gene rapid sequencer in a new field – customizing skin care whey on the basis of each person's DNA, which may be the best beauty product for anti-aging. This skin care whey is called Geneu and has been shown to reduce fine lines and wrinkles by up to 30% in 12 weeks after 18 months of clinical trials. This is also the first time that scientists have tailor-made anti-aging skin care products for individuals, which may completely change people's skin care habits. July Gene editing technology "deletes" HIV. Once HIV (HIV) invades human cells, it will remain there. The HIV virus will embed its deadly genome into the infected person's DNA, forcing the infected person to The rest of his life is treated. Researchers at the Temple University School of Medicine in Philadelphia, USA, have for the first time found a way to completely remove HIV from human cells through editing techniques. This breakthrough marks the first time that efforts to remove potential HIV-1 viruses from human cells have succeeded – this can also treat other potential infections. However, it is currently not possible to enter clinical applications. Electric Hydraulic Operating Table
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