shock! The "human brain" in the culture dish, developed like a 5-week baby
Release date: 2015-08-24 Recently, at the 2015 Military Health System Research Symposium conference held in Florida, scientists at Ohio State University said that they have developed a nearly complete brain in a petri dish, which is equivalent to a five-week fetal brain. Maturity. The brain-like organ is reprogrammed from adult skin cells and is by far the most complete human brain model. Although it is only the size of a pencil eraser, it has an identifiable structure and includes 99% of the genes present in the human fetal brain. Rene Anand, a professor of biochemistry and pharmacology at Ohio State University, said that the establishment of this brain model enables faster and more definitive detection of experimental drugs before starting clinical trials, thereby promoting the genetic and environmental impacts of central nervous system diseases. Including Alzheimer's disease, Parkinson's disease and so on. Professor Anand has been working on the relationship between nicotine receptors and central nervous system diseases, but after many failures in studying autism drugs in rodents, he began to turn to the study of human neurobiological models. After four years of stem cell engineering, he established a "replica" of the human brain. After transforming adult skin cells into pluripotent stem cells, they can be reprogrammed into any body tissue. However, the human brain has been difficult to overcome because of its enormous complexity. In this study, Anand distinguishes cells that can develop into neural tissue by techniques that are cultivated in a device that mimics the uterine environment. The brain model developed by high-resolution imaging revealed that it has functional neurons, axons, dendrites, astrocytes, oligodendrocytes, and microglia; A marker of cells that typically excite and inhibit function. The model that develops into a five-week fetal brain maturity takes 15 weeks, and the researchers will continue to develop the model for 12 weeks and observe the changes. Anand said: "If you let the model develop for 16-20 weeks, you may complete the development of the missing 1% gene. But these are still uncertain." It is worth noting that the release of this study has attracted a lot of attention. Some peers believe that the technology must be under strict supervision. But Anand said that the brain has no consciousness and does not think, so there is no moral problem in the research. Source: Bio-Exploration Pain Relief Patch(Pain Areas)
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