Do you know the application of magnetic stirrer in pharmaceutical equipment?
The agitator is a device for forcibly convecting and uniformly mixing liquid and gaseous media, and is widely used in the chemical, food, dye, cosmetics, and pharmaceutical industries. Up to now, the application of the agitator has become more and more diversified and specialized, and has been continuously improved step by step. The type, size and speed of the agitator have an effect on the distribution of the agitation power between the overall flow and the turbulent pulsation. In general, the power distribution of a turbine agitator is advantageous for turbulent pulsation, while a propeller agitator is advantageous for overall flow. For the same type of agitator, under the same power consumption conditions, the large-diameter, low-speed agitator, the power is mainly consumed by the overall flow, which is conducive to macroscopic mixing. Small-diameter, high-speed agitator, power is mainly consumed by turbulent pulsation, which is conducive to micro-mixing. Since biopharmaceuticals put forward higher requirements for the sterility and risk control of the agitator shaft seal, the industrial magnetic stirrer came into being in Sweden in the 1980s. Now, the lower magnetic stirrer has become the mainstream of the market, and continues to develop in the direction of simplicity, high torque, large shear force or very low shear force, safe bearing material, easy online cleaning and online sterilization. For example, a lower magnetic stirrer for a bioreactor, a lower magnetic stirrer for a high shear force, and the like. Is it possible to prove that the stirrer can be cleaned online and sterilized online, and the bearing material safety has become the gold standard before the selection of biopharmaceutical blenders? The working principle of the industrial magnetic stirrer is: two magnetic steels inside and outside, separated by an isolation sleeve, and the magnetic coupling between the inner and outer magnetic steels after driving by the motor achieves the purpose of transmission. Used in the most pump classes, the magnetic pump can achieve complete leak-free and energy conversion is most efficient. The upper magnetic stirrer corresponds to the upper magnetic stirrer, and the application field is limited because the risk of the shaft seal is still not completely removed. Magnetic stirrer application Desktop magnetic stirrers and magnetic rods have been widely used, but limited to research and development, small-scale levels, people often have the illusion of magnetic stirrers, that the magnetic stirrer is weak, low power, can not be used for large volume, and Dead ends, online cleaning (CIP) and online sterilization (SIP), however, this view has long been overturned in real-world applications. At present, the lower magnetic stirrer can be adapted to a maximum of 40t of water, even larger, and there are many types of applications. From the structure point of view, the general magnetic stirrer consists of a rotor with a female bearing; a male bearing, a welded bottom plate, and a motor. There are several permanent magnets (not ring) in the motor drive head. There are also the same number of permanent magnets in the corresponding positions in the rotor. The polarity just attracts each other. When installed, the permanent magnets in the motor drive head and the rotor are mutually The magnetic coupling between the motor drives the head to operate, and the magnetic force drives the rotor to operate. The two are completely separated by the tank bottom plate, and no mechanical transmission shaft runs through the tank. The installation location is often located at the bottom of the tank bottom, assembled according to the manufacturer's installation instructions, the position and manhole / hand hole is facing the bottom of the tank, avoiding the installation position of the tank bottom valve, so designed to form eddy currents and Turbulent flow, in order to achieve better mixing effect, experts have done experiments in this area, there are specific parameters for reference, of course, this also with the tank height to diameter ratio, solution properties, viscosity, mixing speed, blender Type and other factors are related. The advantages of the lower magnetic stirrer are obvious compared to the mechanical stirrer installed on the top of the tank: Bottom agitator - can be stirred to a low level volume! Especially suitable for high value-added aseptic products; No mechanical seal - no risk of cross-contamination and leakage of lubricants; No baffle required - more efficient mixing, more efficient online cleaning; Only one spray ball, efficient CIP and SIP, easy to verify; Overall purchase and maintenance costs are low; Easy to maintain. Active Ingredient,Main Component,Flavone,Saponins Shaanxi Zhongyi Kangjian Biotechnology Co.,Ltd , https://www.zhongyibiotech.com