PNAS Medical New Technology: Customize 3D printed cartilage with anti-inflammatory effects using stem cells
In order to treat worn and inflamed hip joints without surgery, scientists induced stem cells to be programmed to grow into new cartilage on a 3D stent like a hip femoral head. At the same time, gene therapy can also activate new cartilage to release anti-inflammatory molecules to prevent arthritis. relapse. The work was done by researchers at the University of Washington School of Medicine and published in the international academic journal PNAS. The technology uses a 3D biodegradable synthetic scaffold that can be tailored to the exact shape of the patient's joints, using stem cells in the adipose tissue beneath the patient's skin to induce cartilage, covering it on a 3D scaffold. Obtain new articular cartilage. New cartilage is then implanted into the inflammatory hip surface, and the hip joint is re-covered with living tissue, thereby eliminating arthritis pain, delaying or even eliminating the need for joint replacement surgery in some patients. In addition, the researchers used gene therapy to insert a gene into the new chondrocytes and activate it with a simple drug that promotes the release of anti-inflammatory molecules and prevents the recurrence of arthritis. "In the presence of inflammation, we can give patients a simple drug that activates our implanted genes to reduce inflammation in the joints, so we can stop the administration at any time to turn off gene expression." Said. Fungi, a large class of chlorophyll - free, can not carry out photosynthesis, heterotrophic lower class of plants. These include bacteria, slime molds and fungi. Their common characteristics are: the plant body has no differentiation of roots, stems and leaves, does not contain chlorophyll and other photosynthetic pigments (except a few photosynthetic bacteria), can not carry out photosynthesis, saprophytic life or parasitic life, that is, heterotrophic life. Most of the reproductive organs are single-cell structures, and the zygotes do not develop into embryos. Ganoderma Lucidum Extract,Lion's Mane mushroom Extract,Chaga Mushroom Extract Xi'an Double H Health Technology Co., Ltd , https://www.xadoubleh.com