New study finds genetic variation associated with major depression

Medical Network May 11 A large-scale international study recently found that 44 genetic variants can increase the risk of major depression. This finding helps to understand the genetic basis of depression and to find new treatments.
The research was published in the journal Nature Genetics. Researchers from the United Kingdom, the United States, and Australia have collected data on more than 135,000 patients with major depression worldwide. After comparative analysis, they have at least some of these 44 variant genes, 30 of which were previously Never been found to be associated with depression.
The researchers say that not all patients have improved after receiving antidepressant medications, and their new findings help explain this phenomenon. In addition, they also found that from the genetic factors, depression and anxiety, schizophrenia, bipolar disorder and other mental illness have certain in common.
Jerome Brin, a researcher at King's College, University of London, believes that the discovery of these genetic variants is important for the treatment of depression, helping to develop new drugs or improve treatments.
Another researcher, Catherine Lewis, said: "This global study is only the first step. We need to further explore the genetic basis associated with depression to understand how genetic and environmental factors work together to increase the risk of depression."
According to data released by the World Health Organization, more than 300 million people worldwide suffer from depression, and only about half of them respond well to existing treatments.

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