Pharmacological action and application range of amlodipine besylate
Introduction: Mainly applicable to the treatment of hypertension. Can be used alone or in combination with other antihypertensive drugs. Can also be applied to the symptomatic treatment of chronic stable angina. Can be used alone or in combination with other anti-angina drugs. It can also be used for the diagnosis or suspicious treatment of vasospastic angina pectoris and coronary heart disease confirmed by angiography. Can be used alone or in combination with other anti-angina drugs. Its wide range of applications, mainly for high blood pressure, cardiovascular diseases. Amlodipine besylate is officially introduced as: dihydropyridine calcium antagonists (calcium antagonists or slow channel blockers). The contraction of the myocardium and smooth muscles depends on extracellular calcium ions entering the cells through specific ion channels. This product selectively inhibits calcium ions from transmembrane into smooth muscle cells and cardiomyocytes. Its effect on smooth muscle is greater than that of myocardium. Alias: Amolodipine, Collaterals. Anesthesia Medical Co., Ltd. , https://www.honestymed.com
The main application of contraction of the myocardium and smooth muscle depends on extracellular calcium ions entering the cell through specific ion channels. The principle is to selectively inhibit calcium ions from transmembrane into smooth muscle cells and cardiomyocytes. The effect on smooth muscle is greater than that of myocardium. Its interaction with calcium channels is determined by the progressive rate of its binding and dissociation at the receptor site, and pharmacological effects are gradually produced. In addition, it is also the peripheral arterial dilator directly acting on vascular smooth muscle, reducing the peripheral vascular resistance, thereby reducing blood pressure.