Unti-Cancer Azd-2281 Lynparza (Olaparib) CAS 763113-22-0

Model NO.: 763113-22-0
Appearance: White Powder
Shipping: FedEx, DHL, EMS, TNT, HK EMS, Eub, Etk
Other Name: Olaparib
Fuction: Muscle Growth
Trademark: zsyh
Transport Package: Foil Bag
Specification: 99%
Origin: Hongkong
HS Code: 134657687
Model NO.: 763113-22-0
Appearance: White Powder
Shipping: FedEx, DHL, EMS, TNT, HK EMS, Eub, Etk
Other Name: Olaparib
Fuction: Muscle Growth
Trademark: zsyh
Transport Package: Foil Bag
Specification: 99%
Origin: Hongkong
HS Code: 134657687
Unti-Cancer Azd-2281 Lynparza (Olaparib) CAS 763113-22-0 
 
Olaparib is a kind of novel poly ADP-ribose polymerase (PARP) inhibitors, including PARP1, PARP2, and PARP3. PARP mediates a DNA-repair mechanism which plays a important role in DNA damage repair and apoptosis, so olaparib specifically targets on the DNA repair mechanism of the targeting cell DNA repair and take effects by attacking the critical vulnerabilities of cancer cells carrying mutations in BRCA1 and BRCA2. Owing to this mechanism, it can be used for the maintenance therapy of patients of severe recurrent ovarian cancer who has breast cancer susceptibility gene (BRCA) mutation as well as being sensitive to platinum drug. 
 
Olaparib Description  

Olaparib product name:laparib (AZD2281, Ku-0059436)
AZD2281 Ku-0059436
Olaparib (AZD2281, Ku-0059436) is a selective PARP1 / 2 inhibitor with an IC50 of 5 nM / 1 nM in cell-free assays, 300-fold stronger than that of Tankyrase-1. Phase 3
Olaparib Chemical Name : 4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
Olaparib CAS :763113-22-0
Olaparib MF:    C24H23FN4O3
Olaparib MW:    434.46
Olaparib Solubility (25°C) : DMSO 86 mg/mL warming (197.94 mM) Water 0.002 mg/mL (0.0 mM) Ethanol <1 mg/mL
Olaparib Stability :-20ºC Powder , 3 years : -80ºC Soluble in solvents 2years
Olaparib Usage:Olaparib is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Recent studies show that Olaparib increases radiosensitivity of a lung tumor xenograft, making it a potential candidate for use in combination with radiotherapy.
 
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Make an order 1.Please let me know the items you are looking for, quantity, and the destination country;
2.You confirm all details, and offer us purchasing order;
3.We send the detail price of our product and offer the suitable shipping method for reference;
4.You confirm the order and pay money 100% in advance and send us the detail address.
5.We arrange the shipment according to your requirements.
6.We offer after-sales service after you receive parcel.
Shipping Provide your addressee info. ( phone number , zip code )
Packing According to different countries and quantity of orders
Lead Time Arranged within 24 hours upon receipt of your payment
Photos Photos of parcel would be offered to tell apart the steroids in advance
Delivery Time Usually 4-6 working days to reach destinations
Tracking number Offered once it is released on the Net .Normally within 24hours upon the receipt of payment.
After-sale service 24/7 online for problems and concern related to steroids
                                             
Other series we offer
 
Testosterones Steroids Injectable Steroids Solution 
Boldenonec  Steroids Mixed Steroids Injections
Nandrolonec Steroids Famale Hormone
Trenbolonec Steroids Sex enhancement hormone 
Drostanolonec Steroids polypeptieds. & HGHs
Primobolans/Methenolone Steroids   SARMS Raw Powder
DHEAs Series Local Anesthetic Agents 
Oral Anabolic Steroid  Weight Loss Steroids
Anti Estrongen Steriods Organic Solvents 
Pharmaceutical Raw Material  


  Unti-Cancer Azd-2281 Lynparza (Olaparib) CAS 763113-22-0 
 
Olaparib is a kind of novel poly ADP-ribose polymerase (PARP) inhibitors, including PARP1, PARP2, and PARP3. PARP mediates a DNA-repair mechanism which plays a important role in DNA damage repair and apoptosis, so olaparib specifically targets on the DNA repair mechanism of the targeting cell DNA repair and take effects by attacking the critical vulnerabilities of cancer cells carrying mutations in BRCA1 and BRCA2. Owing to this mechanism, it can be used for the maintenance therapy of patients of severe recurrent ovarian cancer who has breast cancer susceptibility gene (BRCA) mutation as well as being sensitive to platinum drug. 
 
Olaparib Description  

Olaparib product name:laparib (AZD2281, Ku-0059436)
AZD2281 Ku-0059436
Olaparib (AZD2281, Ku-0059436) is a selective PARP1 / 2 inhibitor with an IC50 of 5 nM / 1 nM in cell-free assays, 300-fold stronger than that of Tankyrase-1. Phase 3
Olaparib Chemical Name : 4-(3-(1-(cyclopropanecarbonyl)piperazine-4-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one
Olaparib CAS :763113-22-0
Olaparib MF:    C24H23FN4O3
Olaparib MW:    434.46
Olaparib Solubility (25°C) : DMSO 86 mg/mL warming (197.94 mM) Water 0.002 mg/mL (0.0 mM) Ethanol <1 mg/mL
Olaparib Stability :-20ºC Powder , 3 years : -80ºC Soluble in solvents 2years
Olaparib Usage:Olaparib is a potent poly(ADP-ribose) polymerase (PARP) inhibitor. Olaparib has been shown to induce significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo. Recent studies show that Olaparib increases radiosensitivity of a lung tumor xenograft, making it a potential candidate for use in combination with radiotherapy.
 
Why Choose Us?
 
Make an order 1.Please let me know the items you are looking for, quantity, and the destination country;
2.You confirm all details, and offer us purchasing order;
3.We send the detail price of our product and offer the suitable shipping method for reference;
4.You confirm the order and pay money 100% in advance and send us the detail address.
5.We arrange the shipment according to your requirements.
6.We offer after-sales service after you receive parcel.
Shipping Provide your addressee info. ( phone number , zip code )
Packing According to different countries and quantity of orders
Lead Time Arranged within 24 hours upon receipt of your payment
Photos Photos of parcel would be offered to tell apart the steroids in advance
Delivery Time Usually 4-6 working days to reach destinations
Tracking number Offered once it is released on the Net .Normally within 24hours upon the receipt of payment.
After-sale service 24/7 online for problems and concern related to steroids
                                             
Other series we offer
 
Testosterones Steroids Injectable Steroids Solution 
Boldenonec  Steroids Mixed Steroids Injections
Nandrolonec Steroids Famale Hormone
Trenbolonec Steroids Sex enhancement hormone 
Drostanolonec Steroids polypeptieds. & HGHs
Primobolans/Methenolone Steroids   SARMS Raw Powder
DHEAs Series Local Anesthetic Agents 
Oral Anabolic Steroid  Weight Loss Steroids
Anti Estrongen Steriods Organic Solvents 
Pharmaceutical Raw Material  


 

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