Peptide Hormone Bivalirudin Trifluoroacetate Powder CAS 128270-60-0
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Detailed Product Description
CAS:128270-60-0
Standard:
Enterprise Standard
Assay:
99% Min.
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Bivalirudin Trifluoroacetate Cas No.: 128270-60-0 Peptide  Human  Growth  Hormone use as unfractionated heparin
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Detailed Product Description
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Product Name
Bivalirudin Trifluoroacetate  Â
Appearance:
white powder
CAS NO.:
128270-60-0
Purity:
99%
 Alias
26:PN:WO2004076484PAGE
Application:
Peptide  Drum
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Quick Detail:
1.Bivalirudin Trifluoroacetate
2.Use as unfractionated heparin and platelet glycoprotein IIb alternative medicine /Â IIIa antagonists
3.Sequence:D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH
4.Alias:126:PN:WO2004076484PAGE:31 claimed protein;Angiomax;BG 8967;Bivalirudin;Hirulog; Hirulog 1
5.Cas No.: 128270-60-0
6.Molecular Formula: C98H138N24O33
7.Use:API
8.Molecular Weight: 2180.29
9.Purity (HPLC): 98.0%min.
10Appearance: White Powder
11.Grade :Pharmaceutical Grade
12..Manufacturer :QuanAo
13.Packing: plastic vial(dedicated for peptide packing) or glass vial, quantity according to customer's detail requirement.
14.Storage:a cool(2~8 ºC) & dry place protected from light, keep package close when not in use.
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Description
Bivalirudin (Angiomax or Angiox, manufactured by The Medicines Company) is a specific and reversible direct thrombin inhibitor (DTI).
Bivalirudin is a DTI that overcomes many limitations seen with indirect thrombin inhibitors, such as heparin. Bivalirudin is a short, synthetic peptide that is potent, highly specific, and a reversible inhibitor of thrombin. It inhibits both circulating and clot-bound thrombin, while also inhibiting thrombin-mediated platelet activation and aggregation. Bivalirudin has a quick onset of action and a short half-life. It does not bind to plasma proteins (other than thrombin) or to red blood cells. Therefore it has a predictable antithrombotic response. There is no risk for Heparin Induced Thrombocytopenia/Heparin Induced Thrombosis-Thrombocytopenia Syndrome (HIT/HITTS). It does not require a binding cofactor such as antithrombin and does not activate platelets. These characteristics make bivalirudin an ideal alternative to heparin.
Bivalirudin clinical studies demonstrated consistent positive outcomes in patients with stable angina, unstable angina (UA), non-ST segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI) undergoing PCI in 7Â major randomized trials
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 Application:
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Bivalirudin is indicated for use as an anticoagulant in patients with unstable angina undergoing percutaneous transluminal coronary angioplasty (PTCA).
Bivalirudin with provisional use of glycoprotein IIb/IIIa inhibitor (GPI) is indicated for use as an anticoagulant in patients undergoing percutaneous coronary intervention (PCI).
Bivalirudin is indicated for patients with, or at risk of HIT/HITTS undergoing PCI.
Bivalirudin is intended for use with aspirin and has been studied only in patients receiving concomitant aspirin.
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Specifications(coa and hplc):Â
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Product name
Bivalirudin Trifluoroacetate
CAS register number
128270-60-0
Molecular formula
C98H138N24O33
Molecular weight
2180.29
Assay
99%
Appearance
White  powder
Single Impurity(HPLC)
1.0%max
Amino Acid Composition
±10% of theoretical
Peptide Content(N%)
≥80.0%
Water Content(Karl Fischer)
≥5.0%
Acetate Content(HPIC)
≤12.0%
Mass Balance
95.0~105.0%
Grade
Pharmaceutical Grade
MS(ESI)
Consistent
Price
Negotiated
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Competitive Advantage:
1. Fast safe and discreet delivery,guarantee to pay compensations
2. High quality products with competitive prices
3. Professional service,small order acceptable
4. Enough stock and prompt delivery
5. Service: Reply quickly ,Tracking number ,Status updates ,Receiving remind ,Good after-sales service.
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Keywords :Â Bivalirudin Trifluoroacetate;
                    As Unfractionated Heparin
                    Peptide  Drum;
                   Peptide  Human  Growth  Hormone;
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Additional:
1 Minimum Order: 20g
2 Packaging: Pack in sterile aluminum foil bag or depends
3 Payment : T/T , Western Union , bank transfer , MoneyGram
4 Shipping :EMS, DHL, FEDEXTNT
5 Delivery Time: Within 7Â days after payment
6 Application: Pharmaceutical and biochemical research
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